Week 10 NFL betting guide, odds, props: AI, expert, model, parlay, DFS season-long fantasy picks revealed [Video]

Backing the Detroit Lions has been a profitable NFL betting strategy this season. Detroit has won six consecutive games and is 7-1 against the spread in 2024. The Lions have also covered the spread in seven straight games on the road dating back to last season. This week, the Lions will take on the Houston Texans on Sunday Night Football. According to the latest Week 10 NFL odds, Detroit is a 3.5-point favorite. Other Week 10 NFL spreads of note include Steelers vs. Commanders (-2.5, 45), 49ers vs. Buccaneers (+6.5, 50.5), and Eagles vs. Cowboys (+7.5, 44). If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 10, SportsLine has you covered with its proven model, AI PickBot and team of experts. They even have one pick that returns a whopping +14000, so be …